APDB: a web server to evaluate the accuracy of sequence alignments using structural information
| Title | APDB: a web server to evaluate the accuracy of sequence alignments using structural information |
| Publication Type | Journal Article |
| Year of Publication | 2006 |
| Authors | Armougom, F, Poirot O, Moretti S, Higgins DG, Bucher P, Keduas V, Notredame C |
| Journal | Bioinformatics |
| Volume | 22 |
| Pagination | 2439-40 |
| Date Published | Oct 1 |
| Accession Number | 17032685 |
| Keywords | Algorithms Amino Acid Sequence Conserved Sequence Internet Molecular Sequence Data Proteins/ chemistry Sequence Alignment/ methods Sequence Analysis, Protein/ methods Sequence Homology, Amino Acid Software User-Computer Interface |
| Abstract | The APDB webserver uses structural information to evaluate the alignment of sequences with known structures. It returns a score correlated to the overall alignment accuracy as well as a local evaluation. Any sequence alignment can be analyzed with APDB provided it includes at least two proteins with known structures. Sequences without a known structure are simply ignored and do not contribute to the scoring procedure. AVAILABILITY: APDB is part of the T-Coffee suite of tools for alignment analysis, it is available on www.tcoffee.org. A stand-alone version of the package is also available as a freeware open source from the same address. |
