<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="6.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Di Tommaso, P.</style></author><author><style face="normal" font="default" size="100%">Moretti, S.</style></author><author><style face="normal" font="default" size="100%">Xenarios, I.</style></author><author><style face="normal" font="default" size="100%">Orobitg, M.</style></author><author><style face="normal" font="default" size="100%">Montanyola, A.</style></author><author><style face="normal" font="default" size="100%">Chang, JM.</style></author><author><style face="normal" font="default" size="100%">Taly, JF.</style></author><author><style face="normal" font="default" size="100%">Notredame, C.</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">T-Coffee: a web server for the multiple sequence alignment of protein and RNA sequences using structural information and homology extension.</style></title><secondary-title><style face="normal" font="default" size="100%">Nucleic acids research</style></secondary-title></titles><dates><year><style  face="normal" font="default" size="100%">2011</style></year><pub-dates><date><style  face="normal" font="default" size="100%">May</style></date></pub-dates></dates><urls><web-urls><url><style face="normal" font="default" size="100%">http://dx.doi.org/10.1093/nar/gkr245</style></url></web-urls></urls><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">This article introduces a new interface for T-Coffee, a consistency-based multiple sequence alignment program. This interface provides an easy and intuitive access to the most popular functionality of the package. These include the default T-Coffee mode for protein and nucleic acid sequences, the M-Coffee mode that allows combining the output of any other aligners, and template-based modes of T-Coffee that deliver high accuracy alignments while using structural or homology derived templates. These three available template modes are Expresso for the alignment of protein with a known 3D-Structure, R-Coffee to align RNA sequences with conserved secondary structures and PSI-Coffee to accurately align distantly related sequences using homology extension. The new server benefits from recent improvements of the T-Coffee algorithm and can align up to 150 sequences as long as 10 000 residues and is available from both http://www.tcoffee.org and its main mirror http://tcoffee.crg.cat.</style></abstract></record></records></xml>