Theory
Occasionally we are engaged in research topics rooted in theory. In the past we have been interested in theoretical study of sympatric speciation and modeling evolution on multidimensional fitness ridges. More recently we have applied Bulmer's 1991 equations to the question of estimating the strength of selection in synonymous sites in primates and for modeling the rate of sequence divergence.
Bibliography
-
. 2010. Rate of sequence divergence under constant selection. Biology Direct. 5(1) Abstract
-
Pubmed. 2008. Hypermutable non-synonymous sites are under stronger negative selection.. PLoS Genet.. 4:e1000281. Abstract
-
. 2006. Selection in Favor of Nucleotides G and C Diversifies Evolution Rates and Levels of Polymorphism at Mammalian Synonymous Sites. J Theor Biol. 240:616-626. Abstract
-
Pubmed. 2001. Multidimensional Epistasis and the Disadvantage of sex. Proc Natl Acad Sci U S A. 98:12089-12092. Abstract
-
Pubmed. 1999. Interactions Among Quantitative Traits in the Course of Sympatric Speciation. Nature. 400:351-354. Abstract
