RNASeq

RECOMB 2012 (16th International Conference on Research in Computational Molecular Biology)

Posted Mon, 2012-01-23 15:50 by Francisco Nuno de Medeiros e Câmara D...
Recomb 2012

RECOMB 2012 (the 16th International Conference on Research in Computational Molecular Biology) will take place in vibrant and beautiful Barcelona from the 21 to 24 April 2012. On this year's conference there will be a strong focus on the computational challenges arising from the extraordinary developments in high throughput technologies. Participants will enjoy a full agenda of keynote talks, paper presentations, and poster sessions, with ample opportunities to get a sample some of the city life of Barcelona. The meeting also overlaps with Sant Jordi (Saint George), on April 23, the patron of Catalonia, and one of the most important civic holidays in the country. In order to get more information on RECOMB 2012 and how to register please click here.

---PLEASE NOTE EARLY REGISTRATION HAS BEEN EXTENDED UNTIL 31 JANUARY 2012!!---

Development of methods to analyze the relationship between chromatin and splicing

The search of sequence prerequisites for nucleosome positioning has been a long-standing problem at the intersection of chromatin structure and gene regulation. With the use of structural information directly related to the primary DNA sequence we propose a new property of natural nucleosome forming sequences, which is inherently related to their intrinsic curvature and its symmetry.

Methods for RNAseq (NGS) data analysis

The field of transcriptomics has recently been given a huge boost from the use of “second” generation high throughput sequencing technologies to sequence RNA samples. Second generation sequencing technologies provide an unprecedented capacity for surveying the nucleic acid content of cells.

IX CRG Annual Symposium (Medical Genome Sequencing: Understanding the genomes of disease)

Posted Wed, 2010-10-06 10:23 by Francisco Nuno de Medeiros e Câmara D...

This symposium was organized by Roderic Guigo and Xavier Estivill and held on the 28-29 Oct 2010. It aimed at establishing a forum for capturing the latest advances in genomic sequencing technologies and its various medical applications. The two-day meeting featured talks by international keynote speakers outlining the current status of medical sequencing, and putting forth the technological challenges ahead. More information on this past event can be obtained by clicking here.

Sequence Mapping and Assembly Assessment Project (SMAAP): RGASP3/dnGASP

Posted Tue, 2010-09-28 14:08 by Francisco Nuno de Medeiros e Câmara D...

SMAAP (RGASP3/dnGASP) is a collaborative effort among researchers to compare and evaluate methods and strategies for de novo genome assembly and RNASeq read alignment using data from 2nd generation sequencing platforms.

Roderic Guigo of the CRG and Ivo Gut of the CNAG will be coordinating the upcoming RGASP3 project.

The rules and all current information concerning RGASP3 and dnGASP can be found on this page.

This project is a collaboration between the CRG, CNAG (Barcelona) and the Sanger Centre (Hixton, UK).

Bioinformatics and Genomics

Group leader:  Roderic Guigó Serra
Investigation of sequence patterns in the genome responsible for functionality

Research in our group focuses on the investigation of the signals involved in gene specification in genomic sequences (promoter elements, splice sites, translation initiation sites, ...). We are interested both in the mechanism of their recognition and processing, and in their evolution. In addition, but related to this basic component of our research, our group is also involved in the development of software for gene prediction and annotation in genomic sequences. Some of our current projects are:

Bioinformatics and Genomics group picture 2011
Eukaryotic SECIS element consensus sequence
ENCODE - RGASP
ENCODE - RGASP
U12Db database screenshot
U12Db database screenshot
preferential positioning of nucleosomes on exonic DNA
screenshot of the SECISaln web-based server at the BGL
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